Centaurium erythraea Rafn. s.l
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The herbal monograph selects and summarises scientific studies regarding efficacy, dosage and safety supporting the therapeutic uses of centaury.
The botanical definition of the herbal drug is the whole or cut, dried flowering aerial parts of Centaurium erythraea Rafn. s.l. including C. majus Zeltner and C. suffruticosum (Griseb.) Ronniger [syn. Erythraea centaurium Pers., C. umbellatum Gilib., C. minus Garsault].
Studies with its main characteristic constituents, the secoiridoid glucosides, are included.
The therapeutic indications are dyspeptic complaints and lack of appetite. Administration of centaury addresses posology; its duration of use; contra-indications; special warnings; special precautions for use; interactions with other medicinal products; other forms of interaction; in pregnancy and lactation; its effects on ability to drive; undesirable effects; overdose.
In vitro experiments with centaury demonstrate antioxidant, radical scavenging and antimicrobial activities as well as a-glucosidase and a-amylase inhibiting properties.
In vivo experiments in animals demonstrate anti-inflammatory, gastroprotective and hepatoprotective activities as well as effects on hyperglycaemia and lipid profiles.
Preclinical safety data for centaury were assessed in toxicity studies.
The selection of literature cited in the monograph is aimed at compiling relevant information about the possible physiological roles of centaury and its major constituents. Examples are given below.
- Centaurium erythraea; Centaurium majus; Centaurium suffruticosum; Erythraea centaurium, Centaurium umbellatum, Centaurium minus
- Centaurii herba
- Dyspeptic complaints; Lack of appetite
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