Pelargonium sidoides DC.; Pelargonium reniforme Curt.
The herbal monograph selects and summarises scientific studies and textbooks regarding efficacy, dosage and safety to support the therapeutic uses of pelargonium.
This herbal drug by definition consists of pelargonium root, dried, unpeeled, usually fragmented, underground organs of Pelargonium sidoides and / or Pelargonium reniforme.
Studies with its main characteristic constituents proanthocyanidins and phenolic acids are included.
The therapeutic indications of pelargonium root are symptoms of upper respiratory tract infections including common cold, such as blocked or runny nose, sore throat and cough.
Administration of pelargonium root addresses dosage; duration of use; contra-indications; special warnings; special precautions for use; interactions with other medicinal products; other forms of interaction; use during pregnancy and lactation; its effects on ability to drive; undesirable effects; overdose.
In vitro experiments with pelargonium root demonstrated its antibacterial and immunomodulatory properties.
In vivo experiments with mice investigated anti-influenza virus activity of a pelargonium root extract.
Controlled clinical studies in humans with pelargonium root liquid extract, demonstrated symptomatic relief in acute bronchitis, in rhinosinusitis and the common cold.
Preclinical safety data were assessed in toxicity studies.
Human safety data were assessed in clinical studies, where gastrointestinal complaints and allergic skin reactions were reported.
The selection of literature cited in the monograph is aimed at bringing together relevant information about the possible physiological roles of pelargonium root and its constituents.
- Pelargonium sidoides DC.; Pelargonium reniforme Curt.
- Pelargonii radix
- Pelargonium root
- Common cold, blocked or runny nose; Sore throat; Cough