Wild Pansy – ESCOP Herbal Monograph 2015


Violae herba cum flore
Wild Pansy (Flowering Aerial Parts)
Published 2015
Price: €20

Format: PDF; Instant Download







The herbal monograph summarises scientific studies and textbooks regarding efficacy, dosage, indications and safety to support the long-standing use of wild pansy.

The herbal drug by definition consists of the dried flowering aerial parts of Viola arvensis Murray and / or Viola tricolor L.

Studies with some of its main characteristic constituents, flavonoids, phenolic acids, carotenoids and cyclotides, are included.

The therapeutic indication is based on human experience and long-standing use: skin disorders such as eczema, seborrhoea, impetigo and acne, as well as cradle cap and nappy-rash of infants.

Administration of wild pansy addresses dosage; duration of use; contra-indications; special warnings; special precautions for use; interactions with other medicinal products; other forms of interaction; its effects on ability to drive; undesirable effects; overdose. In vitro experiments with wild pansy showed antibacterial and antioxidant activities, certain constituents exhibited cytotoxic activity against cancer cell lines.

In vivo experiments in animals demonstrated anti-nociceptive, anti-inflammatory and diuretic activities, in rats improvement of induced eczema was described.

There are no reports about undesirable effects by wild pansy.

The selection of literature cited in the monograph is aimed at bringing together relevant information about the possible pharmacological properties of wild pansy. Examples are given below.


  • Viola arvensis Murray; Viola tricolor L.
  • Violae herba cum flore
  • Wild Pansy, Heartsease
  • Acne; Eczema; Impetigo; Nappy rash


– Franz G. Untersuchungen über die Schleimpolysaccharide von Tussilago farfara L., Symphytum officinale L., Borago officinalis L. und Viola tricolor L. Planta Med 1969;17:217-20. http://dx.doi.org/10.1055/s-0028-1099849
– Göransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P. Seven novel macrocyclic polypeptides from Viola arvensis. J Nat Prod 1999;62:283-6. http://dx.doi.org/10.1021/np9803878
– Piana M., Silva MA, Trvisan G, de Brum TF, Silva CR, Bolignon AA, Oliveira SM, Zadra M et al. Antiinflammatory effects of Viola tricolor.gel in a model of sunburn in rats and the gel stability study. J Ethnopharmacol 2013;150:458-65. http://dx.doi.org/10.1016/j.jep.2013.08.040
– Sadeghnia HR, Hesari TG, Mortazavian SM, Mousavi SH, Tayarani-Najaran Z, Ghorbani A. Viola tricolor induces apoptosis in cancer cell and exhibits antiangiogenic activity in chicken chorioallantoic membrane. Biomed Res Int 2014;2014:625792. http://dx.doi.org/10.1155/2014/625792
– Vukics V, Kery A, Bonn GK, Guttman A. Major flavonoid components of heartsease (Viola tricolor L.) and their antioxidant activities. Anal Bioanal Chem 2008b;390:1917-25. http://dx.doi.org/10.1007/s00216-008-1885-3
– Witkowska-Banaszczak E, Bylka W, Matlawska I, Goslinska O, Muszynski Z. Antimicrobial activity of Viola tricolor herb. Fitoterapia 2005;76:458-61. http://dx.doi.org/10.1016/j.fitote.2005.03.005
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