Wild Thyme – ESCOP Herbal Monograph 2014
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The herbal monograph selects and summarises scientific studies and textbooks regarding efficacy, dosage and safety to support the therapeutic uses of wild thyme.
The definition of the herbal drug is the whole or cut, dried, flowering aerial parts of Thymus serpyllum l.s.l.
Studies with its main characteristic constituent the essential oil with carvacrol as major compound are included.
The therapeutic indication is catarrh of the upper respiratory tract.
Administration of wild thyme addresses posology; its duration of use; contra-indications; special warnings; special precautions for use; interactions with other medicinal products; other forms of interaction; in pregnancy and lactation; its effects on ability to drive; undesirable effects; overdose.
In vitro experiments with wild thyme demonstrate antioxidant, antimicrobial, acetylcholine-esterase inhibiting and anti-proliferative properties.
The selection of literature cited in the monograph is aimed at compiling relevant information about the possible physiological roles of wild thyme and its major constituents. Examples are given below.
- Thymus serpyllum L. s.l
- Serpylli herba
- Wild Thyme
- Catarrh of the upper respiratory tract
EXAMPLE OF REFERENCES:
– Boros B, Jakabová S, Dörnyei Á, Horváth G, Pluhár Z, Kilár F, Felinger A. Determination of polyphenolic compounds by liquid chromatography-mass spectrometry in Thymus species. J Chromatogr A 2010;1217:7972-80. http://dx.doi.org/10.1016/j.chroma.2010.07.042
– Bozkurt E, Atmaca H, Kisim A, Uzunoglu S, Uslu R, Burcak K. Effects of Thymus serpyllum extract on cell proliferation, apoptosis and epigenetic events in human breast cancer cells. Nutr Cancer 2012;64:1245-50. http://dx.doi.org/10.1080/01635581.2012.719658
– Hussain AI, Anwar F, Chatha SAS, Latif S, Sherazi STH, Ahmad A, Worthington J, Sarker SD. Chemical composition and bioactivity studies of the essential oils from two Thymus species from the Pakistani flora. LWT Food Sci Technol 2013;50:185-92. http://dx.doi.org/10.1016/j.lwt.2012.06.003
– Komes D, Belščak-Cvitanović A, Horžić D, Rusak G, Likić S, Berendika M. Phenolic composition and antioxidant properties of some traditionally used medicinal plants affected by the extraction time and hydrolysis. Phytochem Anal 2011;22:172-80. http://dx.doi.org/10.1002/pca.1264
– Rasooli I, Mirmostafa SA. Antibacterial properties of Thymus pubescens and Thymus serpyllum essential oils. Fitoterapia 2002;73:244-50. http://dx.doi.org/10.1016/S0367-326X(02)00064-3
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