Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity

The reduction of inflammation in obese people is an important intervention to avoid complications and comorbidities. In this randomized, double-blind, placebo-controlled clinical study, 51 obese adults were included, with a mean age of 45 years, and an average body mass index of 36 Kg/m². The administration of an aged garlic extract (3.6 g/day) for 6 weeks has shown an anti-inflammatory effect, characterized by a reduction in serum levels of IL-67 and TNF-α, accompanied by regulation in the distribution of lymphocytes. This effect was adfitionally accompanied by the reduction of serum levels of LDL (lipid-lowering effect).